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[stem-ebola] Antiviral immune responses of bats: a review.

"[There has been a historical lack of interest in bats from the infectious diseases community and funding agencies because they were thought to be of little importance as vectors or reservoirs. Much of our knowledge of bats and viruses is from studies of rabies virus and other lyssaviruses (Calisher et al., 2006).

However, in recent years, many novel viruses of human and veterinary importance have been discovered that are hosted, or suspected to be hosted, by bats. In the 1990s, novel paramyxoviruses, Hendra and Nipah viruses, caused outbreaks of fatal disease in Australia and Malaysia (Murray et al., 1995; Chua et al., 2000). Both viruses are hosted by species of pteropid bats. Severe acute respiratory syndrome, caused by a coronavirus, was identified during an outbreak in China and Hong Kong in the early 2000s.

Subsequent research has indicated its ancestor is a batborne virus (Lau et al., 2005; Li et al., 2005). Also in the 2000s, Marburg virus was demonstrated to be hosted by fruit bats, and there is compelling evidence that ebolaviruses are also hosted by fruit bats (Leroy et al., 2005; Towner et al., 2009)."

doi#: 10.1111/j.1863-2378.2012.01528.x

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