Profile profile = null;
    try {
      ResourceSet resourceSet = new ResourceSetImpl();
      profile = (Profile)EcoreUtil.getObjectByType(
        resourceSet.getResource(RegisteredProfile.getRegisteredProfile("MyProfile").uri, true)
          .getContents(), UMLPackage.Literals.PROFILE);
    }
    catch (Exception e) {
      e.printStackTrace();
    }
    
    System.out.println("Profile is defined = " + profile.isDefined() + "\nStereotypes:");
    for (Stereotype s : profile.getOwnedStereotypes())
      System.out.println("   " + s.getName());
    
    Model testModel = UMLFactory.eINSTANCE.createModel();
    testModel.setName("testModel");
    testModel.applyProfile(profile);
    
    System.out.println("Profile applied to model = " + testModel.isProfileApplied(profile));
    
    Package testPackage = testModel.createNestedPackage("testPackage");
    Class testClass = testPackage.createOwnedClass("testClass", false);
    
    System.out.println("Applicable Stereotypes = " + testClass.getApplicableStereotypes().size());

Profile is defined = true
Stereotypes:
   Friends
   Struct Extension
   Struct
   Enum Extension
   Fields
   Enum
   Clazz Extension
   Relation
   Instance
   Clazz
   Instance Extension
Profile applied to model = true
Applicable Stereotypes = 0